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Some drugs, like insulin, may interfere with the body's lipase system. This kind of interaction seems, however, to be of only limited clinical importance.
Heparin given in clinical doses causes a transient release of lipoprotein lipase into the circulation. This may result initially in increased plasma lipolysis followed by a transient decrease in triglyceride clearance.
Soya-bean oil has a natural content of vitamin K1. This may interfere with the therapeutic effect of coumarin derivatives which should be closely monitored in patients treated with such drugs.
Potassium-containing solutions like OMEGAFLEX Peri Emulsion for Infusion/OMEGAFLEX Special Emulsion for Infusion should be used with caution in patients receiving drugs that increase serum potassium concentration, such as potassium-sparing diuretics (triamterene, amiloride, spironolactone), ACE inhibitors (e.g. captopril, enalapril), angiotensin-II-receptor antagonists (e.g. losartan, valsartan), ciclosporin and tacrolimus.
Corticosteroids and ACTH are associated with sodium and fluid retention.
OMEGAFLEX Peri Emulsion for Infusion/OMEGAFLEX Special Emulsion for Infusion should not be given simultaneously with blood in the same infusion set due to the risk of pseudoagglutination (see also Precautions).
